we’ve put together a collection of the best Enzyme Drain Cleaners that are currently available on the market. To help you find the perfect Enzyme Drain Cleaner among a wide variety of options, we constantly update our collection with new and trending models.

10 Best Enzyme Drain Cleaners

Based on dozens of customer reviews and ratings, the followings are the top 10 best-selling Enzyme Drain Cleaners:

# Preview Product Price
1 Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon) Green Gobbler ENZYMES for Grease Trap & Sewer – Controls Foul Odors & Breaks Down Grease, Paper, Fat… $19.98 View Product
2 AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 2-Pack AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 2-Pack $33.78 View Product
3 Biokleen Bac-Out Enzymatic Drain Cleaner - 32 Ounce (2 Pack) - Enzyme Prevents Clogs, Eco-Friendly, Live Enzyme-Producing Cultures and Plant Extracts, No Artificial Fragrance or Preservatives Biokleen Bac-Out Enzymatic Drain Cleaner – 32 Ounce (2 Pack) – Enzyme Prevents Clogs, Eco-Friendly,… $17.98 View Product
4 Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 1 Gallon - Fresh Breeze Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner – Powerful Cleaning & Odor Eliminating… $20.97 View Product
5 Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon… $27.99 View Product
6 SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors and Helps Prevent Clogged Drains | Septic Tank Safe | 48 Count, Orange Scent SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors… $18.99 View Product
7 Instant Power Professional Enzyme Drain Cleaner, Drainage Clog Remover, 4 Pack, (8881) Instant Power Professional Enzyme Drain Cleaner, Drainage Clog Remover, 4 Pack, (8881) $69.66 View Product
8 48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers 48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe… $13.99 View Product
9 Natural Elements Drain & Septic Treatment | Enzyme and Bacteria Drain Cleaner and Clog Remover | 2 Lb Natural Elements Drain & Septic Treatment | Enzyme and Bacteria Drain Cleaner and Clog Remover | 2… $29.99 View Product
10 Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance. Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner,… $24.98 View Product

Top Rated Enzyme Drain Cleaner Reviews

Since we’ve mentioned 10 different models of Enzyme Drain Cleaners on the above list, it may be difficult for you to find the right one for your needs. This is why we listed the key features of each of these Enzyme Drain Cleaners below:

1

Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)
Green Gobbler ENZYMES for Grease Trap & Sewer – Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps (1 Gallon)

$19.98
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Product Highlights:

  • RAPID DEGRADATION TECHNOLOGY. Green Gobbler Enzyme Drain Cleaner degrades fats, oils, greases, starches, proteins, cellulose, sludge, and other food waste. Enzymes are a safer alternative to sodium hydroxide and other caustic chemicals.
  • REDUCE PUMP-OUT FREQUENCY. Enzyme Drain Cleaner reduces the frequency of costly septic tank pump outs when used regularly. Increases the efficacy of grease traps by allowing bacteria to work more effectively.
  • TARGETS FOG, EVEN AS pH DECREASES. Green Gobbler Enzyme Drain Cleaner aids in the biological breakdown of organic material inside of drains and tanks. Promotes separation of water phase from FOG phase, thanks to de-emulsifying surfactant.
  • ULTRA-FAST ODOR ELIMINATION. Green Gobbler Enzyme Drain Cleaner eliminates odors associated with drain lines, lift stations, sewers, septic tanks, leach fields, cesspools, grease traps, and grease interceptors.
  • GUARANTEED, OR YOUR MONEY BACK. Green Gobbler’s conscious creations are safer, stronger, and more effective than caustic chemicals. 30-day money back guarantee. Your satisfaction is guaranteed.
2

AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 2-Pack
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 2-Pack

$33.78
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Product Highlights:

  • 2-pack of of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments; 1 gallon bottles
  • Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
  • Ideal for commercial properties, retail, and hospitality
  • Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
  • Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
3

Biokleen Bac-Out Enzymatic Drain Cleaner - 32 Ounce (2 Pack) - Enzyme Prevents Clogs, Eco-Friendly, Live Enzyme-Producing Cultures and Plant Extracts, No Artificial Fragrance or Preservatives
Biokleen Bac-Out Enzymatic Drain Cleaner – 32 Ounce (2 Pack) – Enzyme Prevents Clogs, Eco-Friendly, Live Enzyme-Producing Cultures and Plant Extracts, No Artificial Fragrance or Preservatives

$17.98
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Product Highlights:

  • PREVENTS DRAIN CLOGS AND ELIMINATES ODORS: Bac-Out Drain Care prevents clogs, and eliminates tough odors. Its gel coating action thoroughly coats pipes to treat slow drains
  • KEEPS PETS AND KIDS IN MIND: Bac-Out Drain Care leaves no harsh fumes or residue, just cleaner pipes and less odor.
  • BIO-ACTIVE FORMULA: A unique blend of live enzyme cultures breakdown and absorb organic material. It’s a more natural way to remove buildup and stinky odors.
  • PLANT-BASED PRODUCT: Bac-Out uses a plant-based, eco-friendly solution with no artificial fragrances or dyes. Our products never contain phosphates, chlorine, ammonia, or brighteners.
  • NEVER TESTED ON ANIMALS AND MADE IN THE USA: Biokleen products are never tested on animals, use biodegradable ingredients and are proudly manufactured in America
4

Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner - Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces - 1 Gallon - Fresh Breeze
Zeiff Pro-Grade Multi-Purpose Probiotic Enzyme Cleaner – Powerful Cleaning & Odor Eliminating Formula For Professional & Home Surfaces – 1 Gallon – Fresh Breeze

$20.97
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Product Highlights:

  • Pro Grade Clean – Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether you’re a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
  • Powerful Cleaning Performance – Our proprietary formulation breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don’t just expect clean, expect Zeiff Clean! You’ll know it when you see it, clean you didn’t even know exists
  • Multi-Purpose Enzyme Cleaner – The special blend of bacterial enzymes, detergent and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines and downpipes, and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
  • Deodorizer & Odor Eliminator – Highly concentrated bacterial digestant for grease, stains, oils, & organic waste. Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness, with a subtle fresh breeze that instantly refreshes any space with a pleasant aroma
  • Safe & Effective – Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA
5

Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White
Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White

$27.99
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Product Highlights:

  • Heavy duty bio-enzyme formula for opening up tough clogged drains
  • Breaks down and liquifies suspended solids like fats, oils, greases and other proteins
  • Eliminates foul odors
  • Use to maintain drain traps, waste treatment plants and other drain systems
  • White milky emulsion with a pleasant scent
6

SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors and Helps Prevent Clogged Drains | Septic Tank Safe | 48 Count, Orange Scent
SANI 360° Sani Sticks Drain Cleaner and Deodorizer | Non-Toxic, Enzyme Formula to Eliminate Odors and Helps Prevent Clogged Drains | Septic Tank Safe | 48 Count, Orange Scent

$18.99
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Product Highlights:

  • SMART CLEANING: Sani Sticks cleaner, deodorizer and clog preventer are a powerful, safe and efficient way to eliminate embarrassing, foul odors from drains and helps to prevent clog backups in sinks and showers. Its non-toxic formula is gentle and safe on septic tanks and is available in multiple scents and count varieties.
  • SMART CLEANING: Sani Sticks cleaner, deodorizer and clog preventer are a powerful, safe and efficient way to eliminate embarrassing, foul odors from drains and helps to prevent clog backups in sinks and showers. Its non-toxic formula is gentle and safe on septic tanks and is available in multiple scents and count varieties.
  • ONE STICK IS ALL IT TAKES: Made with powerful, natural enzymes, each Sani Stick slowly releases a super concentrated blend of powerful enzymes that will eliminate organic deposits and grease build up for 30 days. Just one Sani Stick a month is all that is needed.
  • INNOVATIVE DESIGN: Sani Sticks drain deodorizer and cleaners are thin, cylindrical and only 6.3 inches long making them ideal for homes and businesses. 100% safe for all types of plumbing, the stick rests in the pipe-trap and slowly releases a blend of enzymes that break down food, grease, oil and other organic materials.
  • SAFE TO USE ANYWHERE: Because these odor eliminating drain sticks are non-toxic and use enzymes to clean, they are safe to use in all drains from the bathroom to the kitchen.
  • MONEY SAVER: Avoid embarrassing smells and nasty water build up all while saving time and money. Rather than hiring a plumber or purchasing drain snakes, simply insert one stick a month into all your drains to keep water flowing and drains smelling fresh.
7

Instant Power Professional Enzyme Drain Cleaner, Drainage Clog Remover, 4 Pack, (8881)
Instant Power Professional Enzyme Drain Cleaner, Drainage Clog Remover, 4 Pack, (8881)

$69.66
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Product Highlights:

  • CLEANS AND DEODORIZES: Bad odors in your kitchens and restrooms could indicate that your drain system is clogged; Instant Power clogged drain cleaner removes blockages, clears odor-causing build-up
  • CLEANS AND DEODORIZES: Bad odors in your kitchens and restrooms could indicate that your drain system is clogged; Instant Power clogged drain cleaner removes blockages, clears odor-causing build-up
  • EFFECTIVE CLOG REMOVER: Our clog remover uses enzymes to breakdown and rinse away grease, food particles, and other materials that get stuck in your drainage over time
  • REDUCES COST: Our drain clog remover reduces drain blockage emergencies that disrupt business operations and minimizes the need for frequent grease trap pumping
  • NO HARSH CHEMICALS: Instant Power Enzyme Drain Cleaner does not use harmful acids and caustic ingredients; It contains powerful enzymes that clear clogs but is safe on your pipes and drainage
  • ECO-FRIENDLY: Our environmentally friendly formula will digest fats, oils, and greases along with other organic waste that accumulate in drains and grease traps
8

48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers
48PCS Drain Cleaner Sticks Sink Deodorizer Clog Remover Organic Enzyme Drain Cleaner Tank Safe Prevent Expensive Sewage Backups for Kitchen Bathroom Toilet Showers

$13.99
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Product Highlights:

  • 【BRAND EFFECT BUT COST-EFFECTIVE】Exactly the same unclog effect as the brand as seen on TV but more cost-effective. Achieve a fresh smelling drain and avoid the smell with scented drain cleaner sticks, a toxic-free, affordable, user-friendly methods to effectively prevent clogs, dispel unpleasant smell as well as stop clog backups and improve water flow in drains. Ease of use, and low cost.
  • 【BIODEGRADABLE & NATURAL】Perfect for the kitchen sinks, vanity, bathtub, toilet, showers, etc.
  • 【ONE STICK PER MONTH IS OK】 Each drain pipes takes only one cleaner stick measures 6.3 inches strip of organic enzymes. Once been applied, these enzymatic drain cleaners can keep effective as long as one month as they work. Comes in packs of 48, enough for a family use for an entire year. Use it regularly so that keep your kitchen and bathroom drains running smoothly.
  • 【SAVE HUNDREDS OF DOLLARS】Drain cleaner sticks are surely help reduce plumbing costs in a simple, sanitary, yet effective way. Say goodbye to high plumbing costs and the hassle of of using a snake or other devices. Just a couple of dollars, you’ll get excellent clogs removers as well as deodorizers of 3 kind of scents, to help unclog the drains and freshen up your house.
  • 【RELIABLE AFTER SALE SERVICE】 If you don’t have a positive experience for ANY reason, we will do WHATEVER it takes to make sure you are 100% satisfied with your purchase, and we want to make sure we back that up with a risk free ironclad 30-Day Money Back and Ready to Respond within 24 hours.
Sale9

Natural Elements Drain & Septic Treatment | Enzyme and Bacteria Drain Cleaner and Clog Remover | 2 Lb
Natural Elements Drain & Septic Treatment | Enzyme and Bacteria Drain Cleaner and Clog Remover | 2 Lb

$29.99
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Product Highlights:

  • ✅ Contains enzymes and billions of bacteria to combat clogs and keep pipes flowing freely.
  • ✅ Dramatic reduction in volume of organic waste.
  • ✅ Effective Odor Reduction
  • ✅ For Emergency Lateral Line Opening, Use 1 Canister
  • ✅ Enhance the Natural Biology of Cesspools, Septic Tanks, and Drainage Areas
Sale10

Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.
Black Diamond Stoneworks GET SERIOUS Grease Trap Treatment Commercial Enzyme Drain Opener, Cleaner, Odor Control, Trap Cleaning and Maintenance.

$24.98
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Product Highlights:

  • PROFESSIONAL STRENGTH Grease Trap Cleaner and Commercial drain opener.
  • SAVE MONEY & REPAIRS with GET SERIOUS Grease trap Treatment.
  • COMMERCIAL DRAIN CLEANER for slow draining sinks and lines. Keeps Grease Traps & Drains Flowing
  • ENZYME DRAIN OPENER cleans the pipes before the grease trap, grease trap & pipes leaving the trap.
  • ELIMINATES OFFENSIVE ODORS Safe on Pipes & Plumbing.

Video Overview

How to use Green Gobbler Main Line Opener full fair review.

In this video I give a full fair review on the use of Green gobbler Main Line opener. This video will give you a better perspective on how to use this product and …

Final Words

So, these are all of the Best Enzyme Drain Cleaners available on the market. We hope this collection was helpful to find the right Enzyme Drain Cleaner for the money. However, we recommend checking out the features, benefits, and problems of each of these Enzyme Drain Cleaners before taking your decision.